The major research interests of my laboratory are drug resistance in cancer chemotherapy, chemical biology/drug discovery, and translational control in drug response and tumorigenesis.

The laboratory is housed on the 4th floor of the Health Science Building and consists of graduate students, postdoctoral fellows, junior faculty and technical staff. The lab provides an outstanding opportunity for training of summer undergraduate students, graduate students and postdoctoral fellows in the areas of molecular biology, chemical biology, pharmacology, biochemistry, cancer biology, and bio/chemo-informatics.

  • LinkedIn-JT

Recent Publications

Therapeutic Activity of the Lansoprazole Metabolite 5-Hydroxy Lansoprazole Sulfide in Triple-Negative Breast Cancer by Inhibiting the Enoyl Reductase of Fatty Acid Synthase
J Med Chem. 2022 Oct
A novel survivin dimerization inhibitor without a labile hydrazone linker induces spontaneous apoptosis and synergizes with docetaxel in prostate cancer cells
Bioorg Med Chem. 2022 Jul